Browsing by Author "Mendes, Tiago"
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- Memory awareness in patients with major depressive disorderPublication . Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Marôco, João Paulo.; Silva, Dina; Alves, Luísa; Schmand, Ben; Couto, Frederico Simões Do; Figueira, Maria Luísa; De Mendonça, AlexandreSubjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer's Disease (MCI-AD) and healthy controls (HC).
- Memory complaints are frequent but qualitatively different in young and elderly healthy peoplePublication . Ginó, Sandra; Mendes, Tiago; Maroco, João; Ribeiro, Filipa; Schmand, Ben A.; Mendonça, Alexandre de; Guerreiro, ManuelaBackground: Subjective memory complaints are frequently reported by the elderly. There is less information about the characterization of subjective memory complaints in young people. Objective: To determine different memory complaints between young and elderly people with the use of the Subjective Memory Complaints (SMC) scale. Methods: Participants were volunteers attending a health itinerant unit, a blood donor centre, a leisure centre for retired people, a senior citizens college or university. All participants were questioned about their own memory abilities using the SMC scale and assessed for the presence of depressive symptoms. Results: Nine-hundred and forty-six subjects aged 18–92 years were included in the study. The mean total score on the SMC scale was 4.89 +- 3.03, and 75.9% of the participants had at least minor complaints about their memory. Older people had more general memory complaints and reported they were more likely to become transiently confused, whereas younger people reported they were more frequently told by others that they were forgetful and would more often take notes. Conclusions: Memory complaints were frequent both in young and elderly subjects, but the detailed assessment revealed age-related differences in the type of complaints.
- Memory complaints associated with seeking clinical carePublication . Pires, Carolina; Silva, Dina Lúcia Gomes da; Maroco, João; Ginó, Sandra; Mendes, Tiago; Schmand, Ben A.; Guerreiro, Manuela; Mendonça, Alexandre deDiagnosis of mild cognitive impairment relies on the presence of memory complaints. However, memory complaints are very frequent in healthy people. The objective of this study was to determine the severity and type of memory difficulties presented by elderly patients who seek for clinical help, as compared to the memory difficulties reported by subjects in the community. Assessment of subjective memory complaints was done with the subjective memory complaints scale (SMC). The mini-mental state examination was used for general cognitive evaluation and the geriatric depression scale for the assessment of depressive symptoms. Eight-hundred and seventy-one nondemented subjects older than 50 years were included. Participants in the clinical setting had a higher total SMC score (10.3 ± 4.2) than those in the community (5.1 ± 3.0). Item 3 of the SMC, Do you ever forget names of family members or friends? contributed significantly more to the variance of the total SMC score in the clinical sample (18%) as compared to the community sample (11%). Forgetting names of family members or friends plays an important role in subjective memory complaints in the clinical setting. This symptom is possibly perceived as particularly worrisome and likely drives people to seek for clinical help.
- Neuropsychological contribution to predict conversion to dementia in patients withmild cognitive impairment due Alzheimer’s diseasePublication . Silva, Dina Lúcia Gomes da; Cardoso, Sandra; Guerreiro, Manuela; Marôco, J. P.; Mendes, Tiago; Alves, Luísa; Nogueira, Joana Maia; Baldeiras, Ines; Santana, Isabel; Mendonça, Alexandre deDiagnosis of Alzheimer's disease (AD) confirmed by biomarkers allows the patient to make important life decisions. However, doubt about the fleetness of symptoms progression and future cognitive decline remains. Neuropsychological measures were extensively studied in prediction of time to conversion to dementia for mild cognitive impairment (MCI) patients in the absence of biomarker information. Similar neuropsychological measures might also be useful to predict the progression to dementia in patients with MCI due to AD.
- Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive ImpairmentPublication . Alves, Luísa; Cardoso, Sandra; Silva, Dina; Mendes, Tiago; Maroco, J. P.; Nogueira, Joana; Lima, Marisa; Pereira, Miguel Tábuas; Baldeiras, Inês; Santana, Isabel; De Mendonça, Alexandre; Guerreiro, ManuelaPatients diagnosed with amnestic mild cognitive impairment (aMCI) are at high risk of progressing to dementia. It became possible, through the use of biomarkers, to diagnose those patients with aMCI who have Alzheimer's disease. However, it is presently unfeasible that all patients undergo biomarker testing. Since neuropsychological testing is required to make a formal diagnosis of aMCI, it would be interesting if it could be used to predict the amyloid status of patients with aMCI.