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A three-dimensional stereotaxic MRI brain atlas of the cichlid fish oreochromis mossambicus

dc.contributor.authorSimões, José Miguel
dc.contributor.authorTeles, Magda
dc.contributor.authorOliveira, Rui Filipe
dc.contributor.authorVan der Linden, Annemie
dc.contributor.authorVerhoye, Marleen
dc.date.accessioned2013-09-21T13:30:16Z
dc.date.available2013-09-21T13:30:16Z
dc.date.issued2012
dc.description.abstractThe African cichlid Oreochromis mossambicus (Mozambique tilapia) has been used as a model system in a wide range of behavioural and neurobiological studies. The increasing number of genetic tools available for this species, together with the emerging interest in its use for neurobiological studies, increased the need for an accurate hodological mapping of the tilapia brain to supplement the available histological data. The goal of our study was to elaborate a three-dimensional, highresolution digital atlas using magnetic resonance imaging, supported by Nissl staining. Resulting images were viewed and analysed in all orientations (transverse, sagittal, and horizontal) and manually labelled to reveal structures in the olfactory bulb, telencephalon, diencephalon, optic tectum, and cerebellum. This high resolution tilapia brain atlas is expected to become a very useful tool for neuroscientists using this fish model and will certainly expand their use in future studies regarding the central nervous system.por
dc.identifier.citationPlos One, 7 (9), e44086por
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10400.12/2386
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherPublic Library Sciencepor
dc.titleA three-dimensional stereotaxic MRI brain atlas of the cichlid fish oreochromis mossambicuspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSan Franciscopor
oaire.citation.titlePlos Onepor
oaire.citation.volume7por
rcaap.rightsembargoedAccesspor
rcaap.typearticlepor

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