Repository logo
 
Publication

Memory complaints in amnestic mild cognitive impairment: More prospective or retrospective?

dc.contributor.authorMendonça, Alexandre de
dc.contributor.authorFelgueiras, Helena
dc.contributor.authorVerdelho, Ana
dc.contributor.authorCâmara, Sara
dc.contributor.authorGrilo, Cláudia
dc.contributor.authorMaroco, João
dc.contributor.authorPereira, Antonina
dc.contributor.authorGuerreiro, Manuela
dc.date.accessioned2018-05-19T12:47:27Z
dc.date.available2018-05-19T12:47:27Z
dc.date.issued2018
dc.description.abstractObjective: Patients with amnestic Mild Cognitive Impairment (aMCI), usually considered an early stage of Alzheimer's disease, have deficits not only in retrospective memory (RM), that is, recalling of past events, words or people, but also on prospective memory (PM), the cognitive ability of remembering to execute delayed intentions in the future. This study investigated whether patients with aMCI refer more PM complaints as compared with RM complaints, and whether this might depend upon short‐term vs long‐term items or time‐based vs event‐based tasks. Methods: Patients with aMCI (n = 178) and healthy controls (n = 160) underwent the Prospective and Retrospective Memory Questionnaire (PRMQ), a 16‐item instrument to appraise differences between PM and RM complaints, as well as a general mental state examination, a subjective memory complaints questionnaire, objective memory tests, and assessment of depressive symptoms and activities of daily living. Results: Patients with aMCI reported more memory complaints evaluated with the PRMQ (total score = 44.3 ± 10.8) as compared with controls (36.7 ± 9.8, P < 0.001). Using a mixed effect repeated‐measures analysis of covariance (ANCOVA) showed that participants generally referred more retrospective than prospective memory complaints. Patients with aMCI had significantly more complaints on short‐term memory as compared with long‐term memory, and more complaints in time‐based (autoinitiated) as compared with event‐based tasks, than healthy controls. Conclusion: Patients with aMCI reported significantly more difficulties on shortterm memory, presumably reflecting internal temporal lobe pathology typical of Alzheimer's disease, and more complaints on time‐based tasks, which are cognitively very demanding, but did not seem particularly troubled regarding prospective memory.pt_PT
dc.description.sponsorshipFundação para a Ciência e Tecnologia (FCT)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInternational Journal of Geriatric Psychiatry, 1-8. Doi: 10.1002/gps.4886pt_PT
dc.identifier.doi10.1002/gps.4886pt_PT
dc.identifier.issn0885-6230
dc.identifier.urihttp://hdl.handle.net/10400.12/6375
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relationPTDC/EEI‐SII/1937/2014pt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/abs/10.1002/gps.4886pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectEvent basedpt_PT
dc.subjectLong‐term memorypt_PT
dc.subjectMild cognitive impairmentpt_PT
dc.subjectProspective memorypt_PT
dc.subjectRetrospective memorypt_PT
dc.subjectShort‐term memorypt_PT
dc.subjectTime basedpt_PT
dc.titleMemory complaints in amnestic mild cognitive impairment: More prospective or retrospective?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited Statespt_PT
oaire.citation.endPage8pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleInternational Journal of Geriatric Psychiatrypt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
GP, 1-8 (PSYCINFO).pdf
Size:
250.93 KB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.61 KB
Format:
Item-specific license agreed upon to submission
Description: