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- The Importance of sleep fragmentation on the hemodynamic dipping in obstructive sleep apnea patientsPublication . Staats, Richard; Barros, Inês; Fernandes, Dina; Grencho, Dina; Reis, Cátia; Matos, Filipa; Valença, João; Marôco, João Paulo; Almeida, António Bugalho de; Bárbara, CristinaObstructive sleep apnea (OSA) has been associated with non-dipping blood pressure (BP). The precise mechanism is still under investigation, but repetitive oxygen desaturation and arousal induced sleep fragmentation are considered the main contributors.