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Publication
Effects of the antidressant venlafaxine on survival and behaviour of two fish species larvae
Advisor(s)
Abstract(s)
As águas efluentes e residuais transportam organismos, nutrientes e substâncias químicas
que os tratamentos de água não conseguem eliminar. Ao longo do tempo têm sido encontrados
vários fármacos diluídos nas águas efluentes sendo, entre outros, os antidepressivos detectados
frequentemente. Alguns antidepressivos têm sido associados à alteração da fisiologia e
comportamento de espécies marinhas.
Neste estudo, avaliou-se o efeito do antidepressivo venlafaxina na sobrevivência e nos
comportamentos de movimento e alimentação de larvas de duas espécies de peixes marinhos, o
sargo (Diplodus sargus) e a dourada (Sparus aurata). As larvas foram submetidas a uma exposição
aguda por 24 e 48 horas e a duas concentrações de venlafaxina: baixa 0,01 μg/mL) e alta (0,1
μg/mL).
Os resultados obtidos indicam que as espécies Diplodus sargus e Sparus aurata podem ser
genericamente afectadas pela exposição aguda ao antidepressivo venlafaxina. No entanto, alguns
dos efeitos da venlafaxina observados nesta experiência foram ligeiros, por exemplo, a maioria
dos comportamentos de movimento não foram afetados de forma significativa.
Futuramente, devem ser direccionados esforços para investigar os possíveis efeitos de
uma exposição crónica destas espécies a antidepressivos.
Wastewater effluents contain organisms, nutrients and chemical substances that water treatment fails to remove. Several pharmaceuticals have been found diluted in water effluents and antidepressants are frequently detected. Antidepressants have been reported as affecting marine organisms physiology and behaviour. In this study we evaluated the effects of the antidepressant venlafaxine on the survival and on the movement and foraging behaviours of larvae of two marine fish species, white seabream (Diplodus sargus) and gilthead seabream (Sparus aurata). Fish larvae were submitted to acute exposure for 24 and 48 hours under two different venlafaxine concentration treatments, low (0,01 μg/mL) and high concentration (0,1 μg/mL). Overall results showed that commercially important species Diplodus sargus and Sparus aurata, can be generically affected by acute exposure to the antidepressant venlafaxine. However, some of the effects of venlafaxine in this experiment were subtle, for instance, most of movement behaviours were not significantly affected. For future research, efforts should be directed for the potential chronic effects of antidepressants on this fish species.
Wastewater effluents contain organisms, nutrients and chemical substances that water treatment fails to remove. Several pharmaceuticals have been found diluted in water effluents and antidepressants are frequently detected. Antidepressants have been reported as affecting marine organisms physiology and behaviour. In this study we evaluated the effects of the antidepressant venlafaxine on the survival and on the movement and foraging behaviours of larvae of two marine fish species, white seabream (Diplodus sargus) and gilthead seabream (Sparus aurata). Fish larvae were submitted to acute exposure for 24 and 48 hours under two different venlafaxine concentration treatments, low (0,01 μg/mL) and high concentration (0,1 μg/mL). Overall results showed that commercially important species Diplodus sargus and Sparus aurata, can be generically affected by acute exposure to the antidepressant venlafaxine. However, some of the effects of venlafaxine in this experiment were subtle, for instance, most of movement behaviours were not significantly affected. For future research, efforts should be directed for the potential chronic effects of antidepressants on this fish species.
Description
Dissertação de Mestrado
no ISPA – Instituto Universitário para
obtenção de grau de Mestre em Biologia
Marinha e Conservação