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H NMR spectroscopy and MVA to evaluate the effects of Caulerpin-Based diet on diplodus sargus lipid profiles

2018Journal article Restricted access
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dc.contributor.authorDel Coco, Laura
dc.contributor.authorFelline, Serena
dc.contributor.authorGirelli, Chiara
dc.contributor.authorAngilè, Federica
dc.contributor.authorMagliozzi, Laura
dc.contributor.authorAlmada, Frederico José Oliveira de
dc.contributor.authorD’Aniello, Biagio
dc.contributor.authorMollo, Ernesto
dc.contributor.authorTerlizzi, Antonio
dc.contributor.authorFanizzi, Francesco
dc.date.accessioned2018-11-05T19:42:24Z
dc.date.available2018-11-05T19:42:24Z
dc.date.issued2018
dc.descriptionSupplementary Materials: The following are available online at http://www.mdpi.com/1660-3397/16/10/390/s1pt_PT
dc.description.abstractThe biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh quality of some marine species (dietary exposed to C. cylindracea) have been observed, no studies on cause-effect relationships have been carried out. Here, for the first time, through a controlled feeding experiment followed by ¹H NMR Spectroscopy and multivariate analysis (PCA, OPLS-DA), we showed that caulerpin taken with diet is directly responsible of changes observed in metabolic profile of fish flesh, including alteration of lipid metabolism, in particular with a reduction of ω3 PUFA content. The potential of caulerpin to directly modulate lipid metabolism opens up new questions about causal mechanism triggered by algal metabolite also in view of a possible exploitation in the nutraceutical/medical field.pt_PT
dc.description.sponsorshipPON (Programma Operativo Nazionale); Centro Ricerche per la Salute dell’Uomo e dell’Ambiente; Ministry of Education; EU FP7 PERSEUS Projectpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMarine Drugs, 16, 1-12 doi: 10.3390/md16100390pt_PT
dc.identifier.doi10.3390/md16100390pt_PT
dc.identifier.issn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.12/6694
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationPONa3_00334pt_PT
dc.relationPRIN 2009pt_PT
dc.relationPRIN 2012pt_PT
dc.relationEU FP7 PERSEUSpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectBiological invasionpt_PT
dc.subjectCaulerpa cylindraceapt_PT
dc.subjectSecondarymetabolitespt_PT
dc.subjectDiplodus sarguspt_PT
dc.subjectMetabolomicspt_PT
dc.subjectNMR spectroscopypt_PT
dc.titleH NMR spectroscopy and MVA to evaluate the effects of Caulerpin-Based diet on diplodus sargus lipid profilespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlandpt_PT
oaire.citation.endPage12pt_PT
oaire.citation.issue10pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleMarine Drugspt_PT
oaire.citation.volume16pt_PT
person.familyNameAlmada
person.givenNameFrederico
person.identifier.ciencia-id0215-02F9-6D3E
person.identifier.orcid0000-0002-1389-8951
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa19a10df-787c-46d8-8609-e6d2bed22ea3
relation.isAuthorOfPublication.latestForDiscoverya19a10df-787c-46d8-8609-e6d2bed22ea3

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