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Is There Evidence of Crohn’s Disease Exclusion Diet (CDED) in remission of active disease in children and adults? A Systematic Review

2024Journal article Open access
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dc.contributor.authorCorreia, Inês
dc.contributor.authorAlmeida Oliveira, Patricia
dc.contributor.authorAntunes, Maria Da Luz
dc.contributor.authorRaimundo, Maria da Graça
dc.contributor.authorMoreira, Ana Catarina
dc.date.accessioned2024-04-30T19:36:46Z
dc.date.available2024-04-30T19:36:46Z
dc.date.issued2024
dc.description.abstractCrohn’s disease (CD) is an inflammatory bowel disease. Previous research has explored the impact of diet on CD, as specific dietary components can influence gut microbiota and immune responses, contributing to damage in the gastrointestinal tract. The Crohn’s Disease Exclusion Diet (CDED) is based on an exclusion diet; it is a recent dietary approach that is often used alongside partial enteral nutrition (PEN) and aims to induce disease remission by excluding certain dietary components. This study assesses the current evidence for the effectiveness of the CDED + PEN in achieving remission in both children and adults with active CD. Our systematic review followed PRISMA recommendations and was registered in PROSPERO with CRD number 42022335076. The searched databases were PubMed/MEDLINE, Cochrane Library, Scopus, and Web of Science. The included studies were analyzed using Rayyan software, and the risk of bias was assessed with Cochrane RevMan 5.0 software. The primary assessed outcome was clinical remission, evaluated with validated questionnaire scores such as PCDAI, CDAI, or HBI. All analyzed papers yielded promising results. Notably, the CDED + PEN demonstrated better tolerance than exclusive enteral nutrition (EEN), resulting in higher adherence rates. Therefore, the CDED + PEN appears to be a viable alternative for induction remission in active disease for both children and adults with CD.pt_PT
dc.description.sponsorshipFundação para a Ciência e Tecnologia - FCTpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCorreia, I., Oliveira, P. A., Antunes, M. L., Raimundo, M. D. G., & Moreira, A. C. (2024). Is There Evidence of Crohn’s Disease Exclusion Diet (CDED) in Remission of Active disease in children and adults? A Systematic Review. Nutrients, 16(7). https://doi.org/10.3390/nu16070987pt_PT
dc.identifier.doi10.3390/nu16070987pt_PT
dc.identifier.issn17487692
dc.identifier.urihttp://hdl.handle.net/10400.12/9752
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley-Blackwell Publishing Ltdpt_PT
dc.relationUIDB/05608/2020pt_PT
dc.relationUIDP/05608/2020pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCrohn’s diseasept_PT
dc.subjectExclusive enteral nutritionpt_PT
dc.subjectPartial enteral nutritionpt_PT
dc.subjectCrohn’s disease exclusion dietpt_PT
dc.subjectPemissionpt_PT
dc.titleIs There Evidence of Crohn’s Disease Exclusion Diet (CDED) in remission of active disease in children and adults? A Systematic Reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited Statespt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage987pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume16pt_PT
person.familyNameCorreia
person.familyNameAlmeida Oliveira
person.familyNameAntunes
person.familyNameMoreira
person.givenNameInês
person.givenNamePatricia
person.givenNameMaria da Luz
person.givenNameAna Catarina
person.identifier3427010
person.identifier1146970
person.identifier.ciencia-id421B-C686-77E0
person.identifier.ciencia-idC81E-CC41-DFB0
person.identifier.orcid0009-0009-9428-3876
person.identifier.orcid0000-0003-2844-8934
person.identifier.orcid0000-0001-9360-5284
person.identifier.orcid0000-0001-7031-6738
person.identifier.scopus-author-id16234261500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication97078cfa-f4e0-4d20-944b-1fbfe2c75bc8
relation.isAuthorOfPublicationaa285384-2619-4ac9-865e-c92426cb91b9
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relation.isAuthorOfPublication.latestForDiscoveryaedbf10e-27ea-45df-9bdf-d0652c8ee325

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