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Quality of life in patients with mild cognitive impairment

dc.contributor.authorBárrios, Helena
dc.contributor.authorNarciso, Sofia
dc.contributor.authorGuerreiro, Manuela
dc.contributor.authorMaroco, João
dc.contributor.authorLogsdon, Rebecca
dc.contributor.authorMendonça, Alexandre de
dc.date.accessioned2013-10-28T19:47:10Z
dc.date.available2013-10-28T19:47:10Z
dc.date.issued2013
dc.description.abstractBackground: Quality of life (QoL) is affected in patients with dementia, but it is not clear whether it is already disturbed in more initial phases of cognitive decline, like Mild Cognitive Impairment (MCI). Aim: Compare the QoL in MCI patients with controls without cognitive impairment, and ascertain whether there are differences in the reports of QoL made by the subjects and by their informants. Methods: Two hundred participants were enrolled, divided into MCI patients (n¼50), MCI informants (n¼50), recruited from a memory clinic and a dementia outpatient clinic, and controls (n¼50) and controls informants (n¼50), recruited in a family practice clinic. QoL was assessed with the QoL in Alzheimer disease (QOL-AD) scale. Results: The total scores of the QOL-AD questionnaire were 32.1 6.9 for MCI patients self-report, 27.2 6.7 for MCI patients in the opinion of their informants, 35.3 4.9 for controls self-report and 35.6 4.9 for controls in the opinion of their informants. MCI patients had lower QOL-AD scores than controls. The QoL reported by patients with MCI was more favorable than the opinion of their informants. Conclusion: The QoL is affected at early stages of cognitive decline. The QoL reported by patients with MCI is better than the opinion of their informants, similarly to what is known in Alzheimer’s disease patients. QoL appears to be an important domain to be evaluated in aging studies.por
dc.identifier.citationAging & Mental Health, 17, 287-292por
dc.identifier.issn1360-7863
dc.identifier.urihttp://hdl.handle.net/10400.12/2451
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherRoutledgepor
dc.subjectQOL-ADpor
dc.subjectMCIpor
dc.subjectAlzheimer’s diseasepor
dc.subjectCaregiver-reportpor
dc.subjectSelf-reportpor
dc.titleQuality of life in patients with mild cognitive impairmentpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceOxfordshirepor
oaire.citation.endPage292por
oaire.citation.startPage287por
oaire.citation.titleAging & Mental Healthpor
oaire.citation.volume17por
rcaap.rightsembargoedAccesspor
rcaap.typearticlepor

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