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Exploring the role of OXTR gene methylation in attachment development: A longitudinal study

2024Journal article Open access
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dc.contributor.authorCuyvers, Bien
dc.contributor.authorEin‐Dor, Tsachi
dc.contributor.authorHoubrechts, Melisse
dc.contributor.authorFreson, Kathleen
dc.contributor.authorGoossens, Luc
dc.contributor.authorVan Den Noortgate, Wim
dc.contributor.authorVan Leeuwen, Karla
dc.contributor.authorBijttebier, Patricia
dc.contributor.authorClaes, Stephan
dc.contributor.authorTurner, Jonathan
dc.contributor.authorChubar, Viktoria
dc.contributor.authorBakermans‐Kranenburg, Marian J.
dc.contributor.authorBosmans, Guy
dc.date.accessioned2024-05-21T15:10:12Z
dc.date.available2024-05-21T15:10:12Z
dc.date.issued2024
dc.description.abstracthe current study explored longitudinally whether oxytocin receptor gene methyla-tion (OXTRm) changes moderated the association between parental sensitivity changesand children’s attachment changes over three waves. Six hundred six Flemish children(10–12 years, 42.8%–44.8% boys) completed attachment measures and provided sali-vary OXTRm data on seven CpG sites. Their parents reported their sensitive parenting.Results suggest that OXTRm changes hardly link to attachment (in)security changesafter the age of 10. Some support was found for interaction effects between parentalsensitivity changes and OXTRm changes on attachment changes over time. Effects sug-gest that for children with increased OXTRm in the promotor region and decreasedmethylation in the inhibitor region over time, increased parental sensitivity was asso-ciated with increased secure attachment and decreased insecure attachment overtime.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationCuyvers, B., Houbrechts, M., Bosmans, G., Ein-Dor, T., Freson, K., Goossens, L., Bijttebier, P., Van Den Noortgate, W., van Leeuwen, K., Claes, S., Chubar, V., Turner, J., & Bakermans-Kranenburg, M. J. (2024). Exploring the role of OXTR gene methylation in attachment development: A longitudinal study. Developmental Psychobiology, 66(5). https://doi.org/10.1002/dev.22496pt_PT
dc.identifier.doi10.1002/dev.22496pt_PT
dc.identifier.issn19390599
dc.identifier.urihttp://hdl.handle.net/10400.12/9797
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAmerican Psychological Associationpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAttachmentpt_PT
dc.subjectHormonespt_PT
dc.subjectParental carept_PT
dc.titleExploring the role of OXTR gene methylation in attachment development: A longitudinal studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited Statespt_PT
oaire.citation.issue5pt_PT
oaire.citation.titleDevelopmental Psychobiologypt_PT
oaire.citation.volume66pt_PT
person.familyNameCuyvers
person.familyNameHoubrechts
person.familyNamefreson
person.familyNameVan Leeuwen
person.familyNameBijttebier
person.familyNameClaes
person.familyNameBosmans
person.givenNameBien
person.givenNameMelisse
person.givenNamekathleen
person.givenNameKarla
person.givenNamePatricia
person.givenNameStephan
person.givenNameGuy
person.identifier.orcid0000-0003-0648-5953
person.identifier.orcid0000-0001-6128-7154
person.identifier.orcid0000-0002-4381-2442
person.identifier.orcid0000-0002-6628-3483
person.identifier.orcid0000-0002-0648-7388
person.identifier.orcid0000-0002-1175-492X
person.identifier.orcid0000-0001-9057-6027
person.identifier.ridAAF-6095-2020
person.identifier.ridL-8822-2015
person.identifier.scopus-author-id6602915344
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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