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Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement

2016Journal article Restricted access
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dc.contributor.authorMartins, Tânia D.
dc.contributor.authorValentim, Ana M.
dc.contributor.authorPereira, Nuno Marques
dc.contributor.authorAntunes, Luis M.
dc.date.accessioned2016-12-20T19:51:25Z
dc.date.available2016-12-20T19:51:25Z
dc.date.issued2016
dc.description.abstractAnaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal’s welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.pt_PT
dc.description.sponsorshipFundação para a Ciência e a Tecnologia (FCT); European Investment Funds by FEDER/COMPETE/POCI – Operacional Competitiveness and Internacionalization Programmept_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLaboratory Animals, 50, 476-488. Doi: 10.1177/0023677216670686pt_PT
dc.identifier.doi10.1177/0023677216670686pt_PT
dc.identifier.issn0023-6772
dc.identifier.urihttp://hdl.handle.net/10400.12/5159
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSAGE Publicationspt_PT
dc.relationBI/CITAB/UTAD/VET/2015pt_PT
dc.relationOptimizing anaesthesia for adult zebrafish – a practical and animal welfare-based approach
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAnaesthesiapt_PT
dc.subjectAnalgesiapt_PT
dc.subjectRefinementpt_PT
dc.subjectWelfarept_PT
dc.subjectZebrafishpt_PT
dc.titleAnaesthesia and analgesia in laboratory adult zebrafish: A question of refinementpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleOptimizing anaesthesia for adult zebrafish – a practical and animal welfare-based approach
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBPD%2F103006%2F2014/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F04033%2F2013/PT
oaire.citation.conferencePlaceUnited Kingdompt_PT
oaire.citation.endPage488pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage476pt_PT
oaire.citation.titleLaboratory Animalspt_PT
oaire.citation.volume50pt_PT
oaire.fundingStreamFARH
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication0f847eda-d7e7-4d15-862e-7a7a8d1a3281
relation.isProjectOfPublication936722e1-64a1-442c-8d7f-d6cdcf735988
relation.isProjectOfPublication.latestForDiscovery0f847eda-d7e7-4d15-862e-7a7a8d1a3281

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