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- Psychedelic-induced mystical experiences: Effects on purpose in life, ontological addiction and mental healthPublication . Padeiro, João Bernardo Vaz; Torres, NunoPsychedelics have been part of human history for millennia. After a first wave of research into their potential for clinical purposes in the treatment of psychiatric disorders, we are now witnessing a new wave and renaissance of psychedelic research, with new studies suggesting their revolutionary potential in the treatment of a condition of disorders. Psychedelic substances are many and diverse, and their effects may vary widely, ranging from fear and panic to bliss. They can produce mystical-type experiences, which can have life-changing consequences for the individual. As such, we are led to wonder in what way the consumption of psychedelics, and the occurrence of these experiences, may promote changes in feelings of purpose in life and ontological addiction, concepts deeply intertwined with depression and anxiety. In this cross-sectional, correlational and quantitative study we gathered a sample of 221 individuals who responded to the Mystical Experience Questionnaire (MEQ-30), Purpose in Life Short-Form (PIL-SF), Ontological Addiction Scale (OAS-31), General Anxiety Disorder (GAD-7) and Patient Health Questionnaire (PHQ-9). Results showed significant correlations between the occurrence of more intense mystical experiences and higher purpose in life. Purpose in life was correlated with ontological addiction and lower scores of anxiety and depression. To our knowledge, the relationship between these variables is a novel finding in the literature of the field. Lower scores of anxiety were also found among psychedelics users.