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Early social deprivation shapes neuronal programming of the social decisionā€making network in a cooperatively breeding fish

2021Journal article Restricted access
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dc.contributor.authorAntunes, Diogo
dc.contributor.authorTeles, Magda C.
dc.contributor.authorZuellig, Matthew
dc.contributor.authorFriesen, Caitlin N.
dc.contributor.authorOliveira, Rui Filipe
dc.contributor.authorAubinā€Horth, Nadia
dc.contributor.authorTaborsky, Barbara
dc.date.accessioned2021-07-16T13:49:49Z
dc.date.available2022-07-01T00:30:15Z
dc.date.issued2021
dc.description.abstractThe early social environment an animal experiences may have pervasive effects on its behaviour. The social decision-making network (SDMN), consisting of interconnected brain nuclei from the forebrain and midbrain, is involved in the regulation of behaviours during social interactions. In species with advanced sociality such as cooperative breeders, offspring are exposed to a large number and a great diversity of social interactions every day of their early life. This diverse social environment may have life-long consequences on the development of several neurophysiological systems within the SDMN, although these effects are largely unknown. We studied these life-long effects in a cooperatively breeding fish, Neolamprologus pulcher, focusing on the expression of genes involved in the monoaminergic and stress response systems in the SDMN. N. pulcher fry were raised until an age of 2 months either with their parents, subordinate helpers and same-clutch siblings (+F), or with same-clutch siblings only (-F). Analysis of the expression of glucocorticoid receptor, mineralocorticoid receptor, corticotropin releasing factor, dopamine receptors 1 and 2, serotonin transporter and DNA methyltransferase 1 genes showed that early social experiences altered the neurogenomic profile of the preoptic area. Moreover, the dopamine receptor 1 gene was up-regulated in the preoptic area of -F fish compared to +F fish. -F fish also showed up-regulation of GR1 expression in the dorsal medial telencephalon (functional equivalent to the basolateral amygdala), and in the dorsolateral telencephalon (functional equivalent to the hippocampus). Our results suggest that early social environment has life-long effects on the development of several neurophysiological systems within the SDMN.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationAntunes, D., Teles, M..C., Zuellig, M., Friesen, C. N. , Oliveira, R. F., Aubinā€Horth, N. & Taborsky, B.(2021). Earlysocial deprivation shapes neuronal programming of the social decisionā€making network in a cooperatively breeding fish. Molecular Ecology Doi: | Revised: 4 June 2021 | Accepted: 11 June 2021 DOI: 10.1111/mec.16019pt_PT
dc.identifier.doi10.1111/mec.16019pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.12/8241
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley-Blackwell Publishing Ltdpt_PT
dc.subjectCooperative breedingpt_PT
dc.subjectDevelopmental plasticitypt_PT
dc.subjectDopamine receptorpt_PT
dc.subjectEarly social experiencept_PT
dc.subjectGlucocorticoid receptorpt_PT
dc.subjectSocial decision-making networkpt_PT
dc.titleEarly social deprivation shapes neuronal programming of the social decisionā€making network in a cooperatively breeding fishpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited Kingdompt_PT
oaire.citation.endPage15pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleMolecular Ecologypt_PT
person.familyNameAntunes
person.familyNameZuellig
person.familyNameOliveira
person.familyNameTaborsky
person.givenNameDiogo
person.givenNameMatthew
person.givenNameRui
person.givenNameBarbara
person.identifier.ciencia-id611C-50AD-6CE7
person.identifier.orcid0000-0002-5694-0785
person.identifier.orcid0000-0001-7767-8926
person.identifier.orcid0000-0003-1528-618X
person.identifier.orcid0000-0003-1690-8155
person.identifier.ridA-3581-2013
person.identifier.scopus-author-id35561080400
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication091e3a87-0fdd-4469-95ec-6f122b482893
relation.isAuthorOfPublication3101bba8-3fe8-4804-8b59-aae51d19471e
relation.isAuthorOfPublication52f01205-dce9-433b-85c5-6390488b1eee
relation.isAuthorOfPublication40768314-a783-45c6-b716-66982306532b
relation.isAuthorOfPublication.latestForDiscovery40768314-a783-45c6-b716-66982306532b

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