Publication
Social interactions elicit rapid shifts in functional connectivity in the social decision-making network of zebrafish
| dc.contributor.author | Teles, Magda | |
| dc.contributor.author | Almeida, Olinda | |
| dc.contributor.author | Lopes, João Sollari | |
| dc.contributor.author | Oliveira, Rui Filipe | |
| dc.date.accessioned | 2015-11-26T18:44:57Z | |
| dc.date.available | 2015-11-26T18:44:57Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | According to the social decision-making (SDM) network hypothesis, SDM is encoded in a network of forebrain and midbrain structures in a distributed and dynamic fashion, such that the expression of a given social behaviour is better reflected by the overall profile of activation across the different loci rather than by the activity of a single node. This proposal has the implicit assumption that SDM relies on integration across brain regions, rather than on regional specialization. Here we tested the occurrence of functional localization and of functional connectivity in the SDM network. For this purpose we used zebrafish to map different social behaviour states into patterns of neuronal activity, as indicated by the expression of the immediate early genes c-fos and egr-1, across the SDM network. The results did not support functional localization, as some loci had similar patterns of activity associated with different social behaviour states, and showed socially driven changes in functional connectivity. Thus, this study provides functional support to the SDM network hypothesis and suggests that the neural context in which a given node of the network is operating (i.e. the state of its interconnected areas) is central to its functional relevance. | pt_PT |
| dc.description.sponsorship | European Comission; Fundação para a Ciência e a Tecnologia (FCT) | pt_PT |
| dc.identifier.citation | Proceedings of the Royal Society B - Biological Sciences, 282, 20151099. doi: 10.1098/rspb.2015.1099 | pt_PT |
| dc.identifier.doi | 10.1098/rspb.2015.1099 | pt_PT |
| dc.identifier.issn | 0962-8452 | |
| dc.identifier.uri | http://hdl.handle.net/10400.12/4124 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Royal Society Publishing | pt_PT |
| dc.relation | A new integrative framework for the study of fish welfare based on the concepts of allostasis, appraisal and coping styles | |
| dc.relation | Molecular mechanisms and evolutionary implications of social plasticity | |
| dc.relation | SOCIAL MODULATION OF ADULT NEUROGENESIS IN FISH | |
| dc.relation | NEUROENDOCRINOLOGY OF REPRODUCTIVE BEHAVIOUR IN THE AFRICAN CICHLID OREOCHROMIS MOSSAMBICUS: REGULATORY MECHANISMS AND SOCIAL MODULATION OF REPRODUCTION | |
| dc.subject | Social behaviour network | pt_PT |
| dc.subject | Mesolimbic reward system | pt_PT |
| dc.subject | Functional localization | pt_PT |
| dc.subject | Functional connectivity | pt_PT |
| dc.subject | Neural context | pt_PT |
| dc.subject | Zebrafish | pt_PT |
| dc.title | Social interactions elicit rapid shifts in functional connectivity in the social decision-making network of zebrafish | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | A new integrative framework for the study of fish welfare based on the concepts of allostasis, appraisal and coping styles | |
| oaire.awardTitle | Molecular mechanisms and evolutionary implications of social plasticity | |
| oaire.awardTitle | SOCIAL MODULATION OF ADULT NEUROGENESIS IN FISH | |
| oaire.awardTitle | NEUROENDOCRINOLOGY OF REPRODUCTIVE BEHAVIOUR IN THE AFRICAN CICHLID OREOCHROMIS MOSSAMBICUS: REGULATORY MECHANISMS AND SOCIAL MODULATION OF REPRODUCTION | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/265957/EU | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/3599-PPCDT/EXCL%2FBIA-ANM%2F0549%2F2012/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/PIDDAC/SFRH%2FBD%2F44848%2F2008/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F37187%2F2007/PT | |
| oaire.citation.conferencePlace | London | pt_PT |
| oaire.citation.endPage | 9 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | Proceedings of the Royal Society B - Biological Sciences | pt_PT |
| oaire.citation.volume | 282 | pt_PT |
| oaire.fundingStream | FP7 | |
| oaire.fundingStream | 3599-PPCDT | |
| oaire.fundingStream | PIDDAC | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | European Commission | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | article | pt_PT |
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