Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.12/5159
Título: Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement
Autor: Martins, Tânia
Valentim, Ana M.
Pereira, Nuno Marques
Antunes, Luis M.
Palavras-chave: Anaesthesia
Analgesia
Refinement
Welfare
Zebrafish
Data: 2016
Editora: SAGE Publications
Citação: Laboratory Animals, 50, 476-488. Doi: 10.1177/0023677216670686
Resumo: Anaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal’s welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.
Peer review: yes
URI: http://hdl.handle.net/10400.12/5159
DOI: 10.1177/0023677216670686
ISSN: 0023-6772
Aparece nas colecções:BCOMP - Artigos em revistas internacionais

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