Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.12/2386
Título: A three-dimensional stereotaxic MRI brain atlas of the cichlid fish oreochromis mossambicus
Autor: Simões, José Miguel
Teles, Magda
Oliveira, Rui Filipe
Van der Linden, Annemie
Verhoye, Marleen
Data: 2012
Editora: Public Library Science
Citação: Plos One, 7 (9), e44086
Resumo: The African cichlid Oreochromis mossambicus (Mozambique tilapia) has been used as a model system in a wide range of behavioural and neurobiological studies. The increasing number of genetic tools available for this species, together with the emerging interest in its use for neurobiological studies, increased the need for an accurate hodological mapping of the tilapia brain to supplement the available histological data. The goal of our study was to elaborate a three-dimensional, highresolution digital atlas using magnetic resonance imaging, supported by Nissl staining. Resulting images were viewed and analysed in all orientations (transverse, sagittal, and horizontal) and manually labelled to reveal structures in the olfactory bulb, telencephalon, diencephalon, optic tectum, and cerebellum. This high resolution tilapia brain atlas is expected to become a very useful tool for neuroscientists using this fish model and will certainly expand their use in future studies regarding the central nervous system.
Peer review: yes
URI: http://hdl.handle.net/10400.12/2386
ISSN: 1932-6203
Aparece nas colecções:UIE-E - Artigos em revistas internacionais

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